GPR17 抗体 (Intracellular)
Quick Overview for GPR17 抗体 (Intracellular) (ABIN7043149)
抗原
See all GPR17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-232, Intracellular
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原理
- A Rabbit Polyclonal Antibody to GPR17 Receptor
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特异性
- Intracellular, 3rd loop
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- Not recommended for human samples.
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预测反应
- Mouse - identical
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产品特性
- Anti-GPR17 Antibody (ABIN7043149, ABIN7044435 and ABIN7044436) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GPR17 from rat and mouse samples. It is unlikely to recognize the protein from human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RQGPRIEKHLKNK, corresponding to amino acid residues 220-232 of rat GPR17
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亚型
- IgG
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anti-G Protein-Coupled Receptor 17 (GPR17) (C-Term) antibody
Verified GPR17 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 1-36) antibodyGPR17 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 151-262) antibodyGPR17 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (Cytoplasmic Domain) antibodyGPR17 适用: 人, Cow, 马, 猴, Pig, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 230-258) antibodyGPR17 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24874 unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 237-266), (Middle Region) antibodyGPR17 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) antibodyGPR17 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7235376)
Blocking Peptide: (ABIN7235376)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- GPR17 (G Protein-Coupled Receptor 17 (GPR17))
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别名
- GPR17
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背景
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G-protein coupled receptor 17, Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT Receptor, P2Y-like receptor,GPR17 is an orphan receptor that can be double-activated by uracil and cysteinyl-leukotriene (CysLT). It is phylogenetically related to both purinergic P2Y and CysLT receptors. GPR17 belongs to the superfamily of G-protein coupled receptors (GPCRs)4.GPR17 expression is highly detected in the brain, kidney, and heart. In the brain, GPR17 is mainly distributed in white matter, gray matter, subependymal zone, and corpus callosum1.Studies have shown that GPR17 receptor plays an important role in spinal cord injury, myelin sheath injury, cerebral ischemic injury, where its expression is extremely upregulated1,2.GPR17 activation promotes oligodendrocyte differentiation and progression toward mature myelin-forming cells. Thus, GPR17 modulators may be used as therapeutic tools to treat pathologies associated with myelin repair in CNS demyelinating diseases3.
Alternative names: GPR17, G-protein coupled receptor 17, Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT Receptor, P2Y-like receptor -
基因ID
- 767613
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NCBI登录号
- NM_001161415
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UniProt
- Q09QM4
抗原
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