FSHR 抗体 (Extracellular)
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- 抗原 See all FSHR 抗体
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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抗原表位
- AA 128-140, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FSHR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to FSH Receptor
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,human - 12,13 amino acid residues identical
- 产品特性
- Anti-FSHR (extracellular) Antibody is directed against an extracellular epitope of the rat FSH receptor. Anti-FSHR (extracellular) Antibody (ABIN7043134, ABIN7044277 and ABIN7044278) can be used in western blot and live cell imaging applications. It has been designed to recognize the FSH receptor from rat, mouse and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)SNTGIKHLPAVHK, corresponding to amino acid residues 128-140 of rat FSHR
- 亚型
- IgG
- Top Product
- Discover our top product FSHR Primary Antibody
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anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 201-300) antibody
FSHR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 631-695) antibodyFSHR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 18-366) antibodyFSHR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3D5G9 unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 21-100) antibodyFSHR 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 18-120) antibodyFSHR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (N-Term) antibodyFSHR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (N-Term) antibodyFSHR 适用: 人, 大鼠, 猴, Cow, Pig, Bat, 山羊, 马, 兔, 绵羊 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) antibodyFSHR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal FSHR-1400 unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) antibodyFSHR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 278-327) antibodyFSHR 适用: 人 IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7235325)
Blocking Peptide: (ABIN7235325)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- 别名
- FSHR (FSHR 产品)
- 背景
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FSH receptor, Follicle-stimulating hormone receptor, Follitropin receptor, FSHRO,FSH (follicle stimulating hormone) is the central hormone of mammalian reproduction, necessary for gonadal development and maturation at puberty and for gamete production during the fertile phase of life1. Together with LH, this gonadotropin is produced and secreted by the pituitary gland as a highly heterogeneous glycoprotein2. The FSH receptor belongs to the family of G-protein coupled receptors, complex transmembrane proteins characterized by seven hydrophobic helices inserted in the plasma membrane and by intracellular and extracellular domains of variable dimensions depending on the type of ligand3. The intracellular portion of the FSH receptor is coupled to a Gs protein and, upon receptor activation by the hormonal interaction with the extracellular domain it initiates a cascade of events that ultimately leads to the specific biological effects of the gonadotropin.FSH acts by binding to specific receptors, localized exclusively in the gonads. The FSH receptor is expressed by two cell types of the gonad, namely Sertoli cells in the testis, and granulosa cells in the ovarian follicle4.Mutations of FSHR may cause primary or secondary amenorrhea, infertility, premature ovarian failure (POF) and ovarian hyperstimulation syndrome (OHSS)5. Mutations of FSHR may also play a role in the development of granulosa cell tumors of ovaries6.
Alternative names: FSHR, FSH receptor, Follicle-stimulating hormone receptor, Follitropin receptor, FSHRO - 基因ID
- 25449
- NCBI登录号
- NM_000145
- UniProt
- P20395
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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