Ephrin A2 抗体 (Extracellular)
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Quick Overview for Ephrin A2 抗体 (Extracellular) (ABIN7043129)
抗原
See all Ephrin A2 (EFNA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-84, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Ephrin-A2
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat - identical, human - 13,14 amino acid residues identical
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产品特性
- Anti-Ephrin-A2 (extracellular) Antibody (ABIN7043129, ABIN7044257 and ABIN7044258) is a highly specific antibody directed against an epitope of mouse EFNA2. The antibody can be used in western blot, immunohistochemistry, and live cell flow cytometry. It has been designed to recognize EFNA2 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)HYGAPLPPAERMER, corresponding to amino acid residues 71-84 of mouse Ephrin-A2
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亚型
- IgG
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anti-Ephrin A2 (EFNA2) (N-Term) antibody
EFNA2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A2 (EFNA2) antibodyEFNA2 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Ephrin A2 (EFNA2) (Asn188), (cleaved) antibodyEFNA2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A2 (EFNA2) (N-Term) antibodyEFNA2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A2 (EFNA2) (AA 1-213) antibodyEFNA2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ephrin A2 (EFNA2) (C-Term), (cleaved) antibodyEFNA2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A2 (EFNA2) (N-Term) antibodyEFNA2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A2 (EFNA2) (AA 76-125) antibodyEFNA2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:400
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235305)
Blocking Peptide: (ABIN7235305)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Ephrin A2 (EFNA2)
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别名
- EFNA2
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背景
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Synonyms: EPH-related receptor tyrosine kinase ligand 6, LERK6, CEK7-ligand, EFNA2
Description: Eph receptor tyrosine kinases family and their ligands, ephrins, are membrane proteins that primarily regulate cell to cell repulsion and cell adhesion and movement by modulating the organization of the actin cytoskeleton mainly through Rho family GTPases. Eph receptors and ephrin ligand signaling regulaes many aspects of cell interaction in the developing neocortex, including migration and axonal target recognition. Ephrin signaling plays an important role in guiding neurons and their projections during embryonic development1,2.In mammals, the Eph receptor tyrosine kinases family has 14 members that are divided into 2 subclasses, the EphA (A1-A8 and A10) and EphB (B1-B4 and B6). This division is based on the sequence similarity of their extracellular domains. EphA receptors bind to glycosylphosphatidyl inositol-anchored ephrin-A ligands, and EphB receptors bind to transmembrane ephrin-B proteins. The ephrin-A proteins include five members ephrin-A1 to ephrin-A5 whereas ephrin-B proteins include three ephrin-B1 to ephrin-B32,3.Ephrin-A2 protein is abundantly expressed in retinal axons. Mutations in Ephrin-A2 disrupts topographic ordering of projections in the developing visual system. A knockout of ephrin-A2 in adult mice shows focal patches of disorganized neocortical laminar architecture, ranging in severity from reduced neuronal density to a complete lack of neurons1,2.
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基因ID
- 13637
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NCBI登录号
- NM_001405
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UniProt
- P52801
抗原
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