Dopamine Receptor d1 抗体 (Intracellular)
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- 抗原 See all Dopamine Receptor d1 (DRD1) 抗体
- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
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抗原表位
- AA 372-385, Intracellular
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适用
- 大鼠
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宿主
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豚鼠
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克隆类型
- 多克隆
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标记
- This Dopamine Receptor d1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Guinea Pig Polyclonal Antibody to D1 Dopamine Receptor
- 特异性
- Intracellular, C-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse,dog,pig - identical, human - 13,14 amino acid residues identical
- 产品特性
- Guinea pig Anti-D1 Dopamine Receptor Antibody is directed against an epitope of rat D1 Receptor. Guinea pig Anti-D1 Dopamine Receptor Antibody (#) raised in guinea pigs can be used in western blot and immunohistochemistry applications. It has been designed to recognize DRD1 from rat, human and mouse samples. The antigen used to immunize guinea pigs is the same as Anti-D1 Dopamine Receptor Antibody (ABIN7043105, ABIN7044227 and ABIN7044228)) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: SSHHEPRGSISKDC, corresponding to amino acid residues 372-385 of rat DRD1
- 亚型
- IgG
- Top Product
- Discover our top product DRD1 Primary Antibody
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anti-Dopamine Receptor D1 (DRD1) (AA 338-446) antibody
DRD1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 101-200) antibodyDRD1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 11-100) antibodyDRD1 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 338-446) antibodyDRD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (N-Term) antibodyDRD1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (C-Term) antibodyDRD1 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (AA 338-446) antibodyDRD1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (C-Term) antibodyDRD1 适用: 人, 猴, 兔 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (Extracellular Domain) antibodyDRD1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D1 (DRD1) (C-Term) antibodyDRD1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:400
- 说明
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Negative Control: BLP-DR001
Blocking Peptide: BLP-DR001
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))
- 别名
- DRD1 (DRD1 产品)
- 背景
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DRD1, D(1A) dopamine receptor,The D1 dopamine receptor (D1 receptor, DRD1) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and hormone secretion. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinson's disease and Schizophrenia1.All five dopamine receptors belong to the 7-transmembrane domain, G-protein coupled receptor (GPCR) superfamily.Historically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes)1.The D1-like receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity1.The D1 receptor is widely distributed throughout the brain with the highest expression in the cerebral cortex and striatum. In the periphery the D1 receptor has been detected in the adrenal cortex, kidney and heart.Functionally, the D1 receptor has been implicated in the regulation of both locomotor and cognitive functions including the maintaining of spontaneous motor behaviors, the control of working memory and cognition as well as the regulation of craving and reward pathways.In addition, the D1 receptor plays an important role in the pathogenesis of hypertension by regulating epithelial Na+ transport and by interacting with vasoactive hormones/humoral factors, such as aldosterone and angiotensin1,2.
Alternative names: D1 Dopamine Receptor, DRD1, D(1A) dopamine receptor - 基因ID
- 24316
- NCBI登录号
- NM_000794
- UniProt
- P18901
- 途径
- cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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