DLG2 抗体 (AA 336-379)
Quick Overview for DLG2 抗体 (AA 336-379) (ABIN7043102)
抗原
See all DLG2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 336-379
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原理
- A Rabbit Polyclonal Antibody to PSD-93
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特异性
- Between PDZ2 and PDZ3 domains.
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human - 42,44 amino acid residues identical
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产品特性
- Anti- Antibody (ABIN7043102, ABIN7045142 and ABIN7045143) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunoprecipitation, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: GST fusion protein
Immunogen Sequence: GST fusion protein with the sequence VEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSTPY, corresponding to amino acid residues 336-379 of rat Chapsyn-110
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亚型
- IgG
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anti-Discs, Large Homolog 2 (DLG2) (AA 310-420) antibody
DLG2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (N-Term) antibodyDLG2 适用: 人, 大鼠, 小鼠, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (AA 614-648) antibodyDLG2 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB47835 unconjugated
anti-Discs, Large Homolog 2 (DLG2) (N-Term) antibodyDLG2 适用: 人, 大鼠, 小鼠, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (pTyr340) antibodyDLG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (AA 22-37) antibodyDLG2 适用: 人, 大鼠, 小鼠, Hamster WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 3 μg fusion protein per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:1000
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说明
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Negative Control: (ABIN7235223)
Blocking Peptide: (ABIN7235223)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- DLG2 (Discs, Large Homolog 2 (DLG2))
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别名
- DLG2
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背景
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Discs large homolog 2, Dlg2, Chapsyn-110,Chapsyn 110 (also known as PSD-93 and DLG2) is a PDZ containing domain protein that is also a member of the membrane-associated guanylate kinase (MAGUK) family of multi-domain adaptor proteins1,2.PDZ domains are conserved protein domains of about 90 amino acids involved in protein-protein recognition, protein targeting and assembly of multi-protein complexes. The name PDZ derives from the first three proteins in which these domains were identified: PSD-95 (a 95 kDa protein involved in signaling at the post-synaptic density), DLG (the Drosophila melanogaster Discs Large protein) and ZO-1 (the zonula occludens 1 protein involved in maintenance of epithelial polarity)1,2.MAGUKs are scaffolding proteins that comprise several modular protein binding motifs including one or more PDZ domains, a Src homology 3 (SH3) domain, and a catalytically inactive guanylate kinase-like domain1,2.The multidomain nature of PDZ-containing proteins enables them to interact with multiple binding partners and hence organize larger signaling protein complexes.Indeed, Chapsyn 110 has been shown to participate in the postsynaptic density, a dedicated structure formed in postsynaptic nerve terminals that includes a specialized assembly of ion channels, receptors and signaling molecules that are involved in information processing and the modulation of synaptic plasticity1,2.
Alternative names: PSD-93, Discs large homolog 2, Dlg2, Chapsyn-110 -
基因ID
- 64053
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NCBI登录号
- NM_001364
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UniProt
- Q63622
抗原
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