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DPYSL2 抗体 (Intracellular)

Name: DPYSL2 抗体 (Intracellular)
SKU: ABIN7043097
Availability: OutOfStock

This anti-DPYSL2 antibody is a 兔多克隆 antibody detecting DPYSL2 in WB 和 IHC. Suitable for 大鼠.

Western blot analysis of rat brain membrane (lanes 1 and 5), mouse brain membrane (lanes 2 and 6), human CCF-STTGI brain astrocytoma (lanes 3 and 7) and rat PC-12 peochromocytoma (lanes 4 and 8) cell line lysates: - 1-3. (DPYSL2 抗体 (Intracellular))

Expression of CRMP2 in rat spinal cord. (DPYSL2 抗体 (Intracellular))

IHC

2 images

产品编号 ABIN7043097

发货至: 中国

Quick Overview for DPYSL2 抗体 (Intracellular) (ABIN7043097)

抗原

See all DPYSL2 抗体

DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This DPYSL2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product DPYSL2 Primary Antibody

抗原表位
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AA 504-517, Intracellular

原理

A Rabbit Polyclonal Antibody to CRMP-2

特异性

Intracellular

交叉反应

人, 小鼠, 大鼠

预测反应

Mouse,human - identical

产品特性

Anti-CRMP2 Antibody (ABIN7043097, ABIN7044542 and ABIN7044543) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize from rat, mouse, and human samples.

纯化方法

Affinity purified on immobilized antigen.

免疫原

Immunogen: Synthetic peptide
Immunogen Sequence: CEVSVTPKTVTPAS, corresponding to amino acid residues 504-517 of rat CRMP2

亚型

IgG
anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 1-572) antibody
DPYSL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 470-571) antibody
DPYSL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F11 unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (C-Term) antibody
DPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) antibody
DPYSL2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 400-500) antibody
KO Validated DPYSL2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (C-Term) antibody
DPYSL2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (Thr509) antibody
DPYSL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 480-529) antibody
DPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 463-492) antibody
DPYSL2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 33CT11-40-3 unconjugated

anti-Dihydropyrimidinase-Like 2 (DPYSL2) (AA 1-100) antibody
DPYSL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:200

说明

Negative Control: (ABIN7235204)
Blocking Peptide: (ABIN7235204)

限制

仅限研究用
状态

Lyophilized

溶解方式

Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

浓度

1 mg/mL

缓冲液

PBS pH 7.4

储存条件

4 °C,-20 °C

储存方法

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
抗原

DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

别名

DPYSL2

背景

CRMP-2, Collapsin response mediator protein 2, Dihydropyrimidinase-related protein 2, DHPRP2, DRP-2, Dpysl2, Turned on after division 64 kDa protein, TOAD-64, Ulip2, Unc-33-like phosphoprotein 2,Collapsin response mediator protein 2 (CRMP-2, DRP-2), is a kinesin-binding protein and a member of the CRMP family, a novel family of microtubule-associated proteins (MAPs). This family consists of 5 highly conserved phosphorylated proteins: CRMP1-CRMP5. CRMP-2 was originally identified in the regulation of microtubule dimerization. CRMP-2 is the first member of the CRMP family identified in primary neuronal cells1,2.Physiological functions of CRMP-2 protein include regulation of cell surface receptor endocytosis, kinesin-dependent axonal transport, growth cone collapse, polarity and differentiation of developing neurons and neurite outgrowth and the regulation of microtubule dynamics2.Studies suggest that CRMP-2 can modulate neuronal viability through the PI3K/mTOR/S6K pathway. In addition, CRMP-2 expression has been detected in non-neuronal cells such as leukocytes, fibroblasts and neuroblastoma1.Phosphorylation of CRMP-2 on specific Thr and Ser residues inactivates its activity, leading to inhibition of axonal growth and neuronal polarity. Knockdown of CRMP-2 shortens the total dendritic length and decreases dendritic branching3.

Alternative names: CRMP2, CRMP-2, Collapsin response mediator protein 2, Dihydropyrimidinase-related protein 2, DHPRP2, DRP-2, Dpysl2, Turned on after division 64 kDa protein, TOAD-64, Ulip2, Unc-33-like phosphoprotein 2

基因ID

25416

NCBI登录号

NM_001386

UniProt

P47942

途径

Regulation of Cell Size