CNTF 抗体 (C-Term)
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Quick Overview for CNTF 抗体 (C-Term) (ABIN7043070)
抗原
See all CNTF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-177, C-Term
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原理
- A Rabbit Polyclonal Antibody to CNTF
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse - identical
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产品特性
- Anti-CNTF Antibody is directed against an epitope of human CNTF. Anti-CNTF Antibody (ABIN7043070 and ABIN7044789) can be used in western blot, immunohistochemistry and immunocytochemistry applications. It has been designed to recognize CNTF from human, rat and mouse samples. Anti-CNTF Antibody specifically recognizes CNTF and not related cytokines.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)ELSQWTVRSIHDLR, corresponding to amino acid residues 164-177 of human CNTF
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亚型
- IgG
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anti-Ciliary Neurotrophic Factor (CNTF) (C-Term) antibody
CNTF 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 1-200) antibodyCNTF 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-198) antibodyCNTF 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 21-150) antibodyCNTF 适用: 人, 大鼠, 兔 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-198) antibodyCNTF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) antibody (Biotin)CNTF 适用: 大鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Ciliary Neurotrophic Factor (CNTF) (AA 1-200) antibodyCNTF 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: 1:200
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235138)
Blocking Peptide: (ABIN7235138)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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别名
- CNTF
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背景
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Synonyms: Ciliary neurotrophic factor
Description: CNTF is a polypeptide trophic factor, member of the alpha-helical cytokine superfamily1. It was initially purified from the chick eye on the basis of its ability to promote survival of E8 chick ciliary ganglion neurons in culture2. CNTF is synthesized by glia both in the CNS and PNS3 and it has been demonstrated that CNTF is ubiquitously distributed in neurons and glia throughout the rodent brain4. CNTF effects are mediated by a tripartite receptor complex consisting of two signal-transducing subunits (leukemia inhibitory factor receptor, gp130) and a CNTF-specific ligand-binding-subunit (CNTFR)5.CNTF can support the survival of many different cell populations within the PNS and the CNS6. in vitro, CNTF promotes proliferation and neuronal specifications in hippocampal neurons. in vivo, it supports the viability of non-primate motor neurons7, induces sprouting of cholinergic motor neurons8 and delays neural degeneration in genetic models of motor neuron disease9. In addition, it is involved in the development stage of astrocytes and oligodendocytes10.
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基因ID
- 1270
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NCBI登录号
- NM_000614
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UniProt
- P26441
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途径
- JAK/STAT Signaling
抗原
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