CLIC1 抗体 (Intracellular)
Quick Overview for CLIC1 抗体 (Intracellular) (ABIN7043056)
抗原
See all CLIC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 195-208, Intracellular
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原理
- A Rabbit Polyclonal Antibody to CLIC1 Channel
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse - identical
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产品特性
- Anti-CLIC1 Antibody (ABIN7043056 and ABIN7044139) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot and immunocytochemistry applications. It has been designed to recognize CLIC1 from mouse, rat, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RGFTIPEAFRGVHR, corresponding to amino acid residues 195-208 of human CLIC1
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亚型
- IgG
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anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-241) antibody
CLIC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 42-241) antibodyCLIC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (N-Term) antibodyCLIC1 适用: 人, 大鼠, 小鼠, Cow, 山羊, 马, 豚鼠, 兔, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-241) antibodyCLIC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 79-241) antibodyCLIC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 42-241) antibodyCLIC1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) antibodyCLIC1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-242) antibodyCLIC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-242) antibodyCLIC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) antibodyCLIC1 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7235102)
Blocking Peptide: (ABIN7235102)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- CLIC1 (Chloride Intracellular Channel 1 (CLIC1))
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别名
- CLIC1
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背景
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Cl- intracellular channel 1, Nuclear chloride ion channel 27, NCC27, Chloride channel ABP,Chloride intracellular channel (CLIC) is a family of proteins encoded by six different genes (CLIC1-6)1-3.The localization of the various CLIC channels remains elusive and controversial since they can be either found in a soluble form in the cytoplasm or as integral membrane proteins (in intracellular compartments such as the nuclear membrane or the endoplasmic reticulum for example, or associated with the plasma membrane) via their single transmembrane domain1.When membrane associated, CLIC channels indeed function as ion channels (enabling the passage of Cl- ions). Non-channel functions are also attributed to CLICs and include cell cycle regulation, cell differentiation, and apoptosis. These different roles depend on whether CLICs are membrane bound or cytosolic1.CLIC1, which was first identified in nuclear membranes, is detected in the epithelia of airways, the gall bladder, pancreas, stomach, small intestine and colon4. CLIC1 was also found to be expressed in the endothelium where it plays a role in cell growth and migration5.
Alternative names: CLIC1, Cl- intracellular channel 1, Nuclear chloride ion channel 27, NCC27, Chloride channel ABP -
基因ID
- 1192
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NCBI登录号
- NM_001288
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UniProt
- O00299
抗原
-
