CXCR1 抗体 (Extracellular)
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- 抗原 See all CXCR1 抗体
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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抗原表位
- AA 2-16, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to CXCR1 Chemokine Receptor
- 特异性
- Extracellular, N-terminus
- 预测反应
- Specific to human CXCR1
- 产品特性
- Anti-Human CXCR1 (extracellular) Antibody is directed against an extracellular epitope of the human CXCR1. Anti-Human CXCR1 (extracellular) Antibody (ABIN7043037 and ABIN7044163)) can be used for western blot and indirect flow cytometry applications. It has been designed to recognize human CXCR1.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)SNITDPQMW DFDDLN, corresponding to amino acid residues 2-16 of human CXCR1
- 亚型
- IgG
- Top Product
- Discover our top product CXCR1 Primary Antibody
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anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (C-Term) antibody
KO Validated CXCR1 适用: 人 IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 186-280) antibodyCXCR1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 250-350) antibodyCXCR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-50) antibodyCXCR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B8A1 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (N-Term) antibodyCXCR1 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 330-341) antibodyCXCR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 26-38) antibodyVerified CXCR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: BLP-CR011
Blocking Peptide: BLP-CR011
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- 别名
- CXCR1 (CXCR1 产品)
- 背景
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C-X-C chemokine receptor type 1, Interleukin-8 receptor A, IL-8R A, IL8RA, IL-8 receptor type 1, CD181,Chemokine receptors belong to the seven transmembrane domain G-protein coupled receptor superfamily and are differentially expressed in diverse cell types. In leukocytes, chemokines coordinate development, differentiation, anatomic distribution, trafficking, and effector functions and thereby regulate innate and adaptive immune responses.To date, 18 chemokine receptors are known and designated as CXCR1-5, CCR1-11, XCR1, and CX3CR1 based on their specific chemokine preferences.The CXC chemokine receptors specifically bind and respond to cytokines of the CXC chemokine family. CXCR1 and CXCR2 were the first chemokine receptor subtypes to be defined. They are the only known mammalian receptors for ELR+ CXC chemokines [CXC chemokines which contain the tripeptide motif glutamic acid-leucine-arginine (ELR) N-terminal to the first cysteine].CXCR1 and CXCR2 both bind IL-8, with high affinity, they do not bind other types of chemokines. CXCR1 and CXCR2 are the major chemokine receptors expressed on neutrophils. They appear to operate mainly in acute inflammation and innate immunity.
Alternative names: CXCR1, C-X-C chemokine receptor type 1, Interleukin-8 receptor A, IL-8R A, IL8RA, IL-8 receptor type 1, CD181 - 基因ID
- 3577
- NCBI登录号
- NM_000634
- UniProt
- P25024
- 途径
- cAMP Metabolic Process
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