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- 抗原 See all AVPR1B 抗体
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
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抗原表位
- AA 399-412, Intracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AVPR1B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- A Rabbit Polyclonal Antibody to Vasopressin V1B Receptor
- 特异性
- Intracellular, C-terminus
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 （详细）
- Not recommended for human samples.
- 预测反应
- Mouse - 12,14 amino acid residues identical, human - not recommended for use with human sample
- 产品特性
- Anti-Vasopressin V1B Receptor (AVPR1B) Antibody is directed against an epitope of rat Arginine vasopressin receptor 1B. Anti-Vasopressin V1B Receptor (AVPR1B) Antibody (ABIN7042947, ABIN7045337 and ABIN7045338)) can be used in western blot analysis. It has been designed to recognize V1bR from rat and mouse samples. The antibody is not recommended for human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RAKPRPAGSLKDLE, corresponding to amino acid residues 399-412 of rat AVPR1B
- 亚型
- IgG
- Top Product
- Discover our top product AVPR1B Primary Antibody
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anti-Arginine Vasopressin Receptor 1B (AVPR1B) (N-Term) antibody
AVPR1B 适用: 人, 大鼠, 犬, Cow, Pig, 马, 兔, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (Cytoplasmic Domain) antibodyAVPR1B 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 271-320) antibodyAVPR1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) antibodyAVPR1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 343-425) antibodyAVPR1B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 224-284) antibodyAVPR1B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 271-320) antibodyAVPR1B 适用: 人, 大鼠, 小鼠, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (C-Term) antibodyAVPR1B 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (C-Term) antibodyAVPR1B 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: BLP-VR011
Blocking Peptide: BLP-VR011
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- 别名
- AVPR1B (AVPR1B 产品)
- 背景
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V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Arginine vasopressin receptor 1B, Vasopressin V3 receptor,Vasopressin V1b receptor (also called V3R) is a G protein-coupled receptor (GPCR) of the Gq type, thus activating the phospholipase C signaling pathway upon activation. It is part of a family of GPCRs triggered by vasopressin that further include V1R, V2R, oxytocin receptors and purinergic receptors. While V1R and V3R are Gq GPCRs, V2R is coupled to the Gs protein and activates adenylate cyclase1,2.The V1b receptor has an intracellular C-terminal, seven transmembrane domains, and an extracellular N-tail, the transmembrane and extracellular domains are responsible for interacting with agonists and to signal for activation of the coupled Gq receptor1,2.The V1b receptor is mainly detected in the corticotrophs of the anterior pituitary gland in the brain where it regulates the release of adrenocorticotrophic hormone (ACTH) upon stimulation of vasopressin-corticotrophin-releasing hormone conjugates2.V1b KO mice show that the receptor is critical for the functionality of the hypothalamic-pituitary-adrenal axis, and demonstrate its importance in regulating glucose levels. Recent studies have also suggested that lactating rats treated with V1b antagonists, were less nurturing and similarly aggressive compared with untreated rats and that mice with reduced expression of V1b and V1a receptors have shown resistance to jet-lag1,3,4.
Alternative names: Vasopressin V1B Receptor (AVPR1B), V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Arginine vasopressin receptor 1B, Vasopressin V3 receptor - 基因ID
- 100909648
- NCBI登录号
- NM_000707
- UniProt
- P48974
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
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