AQP9 抗体 (Intracellular, N-Term)
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Quick Overview for AQP9 抗体 (Intracellular, N-Term) (ABIN7042945)
抗原
See all AQP9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-19, Intracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 9 Channel
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交叉反应
- 小鼠, 大鼠
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交叉反应 (详细)
- Unlikely to recognize human samples.
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预测反应
- Mouse - 13,16 amino acid residues identical
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产品特性
- Anti-Aquaporin 9 Antibody (ABIN7042945 and ABIN7045206) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize AQP9 from mouse and rat samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)EKDGAKKSLMQRLALK, corresponding to amino acid residues 4-19 of rat AQP9
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亚型
- IgG
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IHC
Negative Control: (ABIN7234783)
Blocking Peptide: (ABIN7234783)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- AQP9 (Aquaporin 9 (AQP9))
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别名
- AQP9
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背景
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Synonyms: AQP9, Aquaglyceroporin-9
Description: Aquaporin 9 (AQP-9) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes.1 The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are permeated primarily by water (AQP-1, AQP-2, AQP4, AQP-5, AQP-6, AQP-8), and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3, AQP-7, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.2AQP-9 is expressed in several tissues including the brain, liver, testis and spleen. In the liver AQP-9 has a central role in glycerol metabolism as demonstrated in experiments using AQP-9 knockout mice: mice deficient in AQP-9 expression showed enhanced plasma levels of glycerol and triglycerides.3
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基因ID
- 65054
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NCBI登录号
- NM_020980
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UniProt
- P56627
抗原
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