Aquaporin 7 抗体 (Intracellular, N-Term)
Our Local Distributor
北京 101111
Quick Overview for Aquaporin 7 抗体 (Intracellular, N-Term) (ABIN7042943)
抗原
See all Aquaporin 7 (AQP7) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 7-24, Intracellular, N-Term
-
原理
- A Rabbit Polyclonal Antibody to Aquaporin 7 Channel
-
交叉反应
- 小鼠, 大鼠
-
预测反应
- 18 amino acid residues identical,Mouse - 15, human - 11
-
产品特性
- Anti-Aquaporin 7 Antibody (ABIN7042943, ABIN7045203 and ABIN7045204) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize from mouse and rat samples, and may recognize the channel from human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- ENIQSVLQKTWVREFLAE, corresponding to amino acid residues 7-24 of rat AQP7
-
亚型
- IgG
-
-
anti-Aquaporin 7 (AQP7) (AA 251-342) antibody
AQP7 适用: 人, 大鼠, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (AA 1-342) antibodyAQP7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) antibodyAQP7 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (AA 1-342) antibodyAQP7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (N-Term) antibodyAQP7 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (C-Term) antibodyAQP7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB: 1:500
FC: The optimal concentration should be determined by the user
ICC: 1:800
IHC: 1:100
IP: The optimal concentration should be determined by the user
-
说明
-
Cited Application: IHC
Negative Control: (ABIN7234775)
Blocking Peptide: (ABIN7234775)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
-
浓度
- 0.8 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- Aquaporin 7 (AQP7)
-
别名
- AQP7
-
背景
-
Synonyms: AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose
Description: Aquaporin 7 (AQP-7) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permeability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-7, AQP-3, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.AQP-7 is expressed in ovary, testis, kidney and adipose tissue.The function of AQP-7 in adipose tissue attracted much interest as mice deficient in AQP-7 developed adult-onset obesity and Type 2 Diabetes. AQP-7 modulates adipocyte glycerol permeability thereby controlling triglyceride accumulation and fat cell size.
-
基因ID
- 29171
-
NCBI登录号
- NM_001170
-
UniProt
- P56403
抗原
-
