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Aquaporin 7 抗体 (Intracellular)

AQP7 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7042943
发货至: 中国
  • 抗原 See all Aquaporin 7 (AQP7) 抗体
    Aquaporin 7 (AQP7)
    抗原表位
    • 16
    • 3
    • 2
    • 2
    • 2
    AA 7-24, Intracellular
    适用
    • 31
    • 21
    • 21
    • 3
    • 3
    大鼠
    宿主
    • 32
    • 1
    克隆类型
    • 33
    多克隆
    标记
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aquaporin 7 antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 13
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)
    原理
    A Rabbit Polyclonal Antibody to Aquaporin 7 Channel
    特异性
    Intracellular, N-terminus
    交叉反应
    小鼠, 大鼠
    预测反应
    18 amino acid residues identical,Mouse - 15, human - 11
    产品特性
    Anti-Aquaporin 7 Antibody (ABIN7042943, ABIN7045203 and ABIN7045204)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize AQP-7 from mouse and rat samples, and may recognize the channel from human samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: ENIQSVLQKTWVREFLAE, corresponding to amino acid residues 7-24 of rat AQP7

    亚型
    IgG
    Top Product
    Discover our top product AQP7 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100

    Application Dilutions Western blot wb: 1:500

    说明

    Cited Application: IHC

    Negative Control: BLP-QP007

    Blocking Peptide: BLP-QP007

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    Aquaporin 7 (AQP7)
    别名
    AQP7 (AQP7 产品)
    背景
    AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose,Aquaporin 7 (AQP-7) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permeability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-7, AQP-3, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.AQP-7 is expressed in ovary, testis, kidney and adipose tissue.The function of AQP-7 in adipose tissue attracted much interest as mice deficient in AQP-7 developed adult-onset obesity and Type 2 Diabetes. AQP-7 modulates adipocyte glycerol permeability thereby controlling triglyceride accumulation and fat cell size.

    Alternative names: Aquaporin 7, AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose
    基因ID
    29171
    NCBI登录号
    NM_001170
    UniProt
    P56403
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