Aquaporin 7 抗体 (Intracellular)
Quick Overview for Aquaporin 7 抗体 (Intracellular) (ABIN7042943)
抗原
See all Aquaporin 7 (AQP7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-24, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 7 Channel
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特异性
- Intracellular, N-terminus
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交叉反应
- 小鼠, 大鼠
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预测反应
- 18 amino acid residues identical,Mouse - 15, human - 11
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产品特性
- Anti-Aquaporin 7 Antibody (ABIN7042943, ABIN7045203 and ABIN7045204) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize from mouse and rat samples, and may recognize the channel from human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: ENIQSVLQKTWVREFLAE, corresponding to amino acid residues 7-24 of rat AQP7
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亚型
- IgG
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anti-Aquaporin 7 (AQP7) (AA 251-342) antibody
AQP7 适用: 人, 大鼠, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (AA 1-342) antibodyAQP7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) antibodyAQP7 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (AA 1-342) antibodyAQP7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (N-Term) antibodyAQP7 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 7 (AQP7) (C-Term) antibodyAQP7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:500
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说明
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Cited Application: IHC
Negative Control: (ABIN7234775)
Blocking Peptide: (ABIN7234775)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Aquaporin 7 (AQP7)
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别名
- AQP7
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背景
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AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose,Aquaporin 7 (AQP-7) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permeability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-7, AQP-3, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.AQP-7 is expressed in ovary, testis, kidney and adipose tissue.The function of AQP-7 in adipose tissue attracted much interest as mice deficient in AQP-7 developed adult-onset obesity and Type 2 Diabetes. AQP-7 modulates adipocyte glycerol permeability thereby controlling triglyceride accumulation and fat cell size.
Alternative names: Aquaporin 7, AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose -
基因ID
- 29171
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NCBI登录号
- NM_001170
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UniProt
- P56403
抗原
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