Aquaporin 1 抗体 (Intracellular)
Quick Overview for Aquaporin 1 抗体 (Intracellular) (ABIN7042932)
抗原
See all Aquaporin 1 (AQP1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 242-260, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 1 Channel
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- mouse,toad (Bufo marinus) - 14, frog (Rana esculenta),Rat,19 amino acid residues identical,cattle, dog - 18,sheep - identical
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产品特性
- Anti-Aquaporin 1 Antibody (ABIN7042932, ABIN7045194 and ABIN7045195) is a highly specific antibody directed against an epitope of the human AQP1 channel. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize AQP1 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KVWTSGQVEEYDLDADDIN corresponding to amino acid residues 242-260 of human AQP1
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亚型
- IgG
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anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 181-269) antibody
AQP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 201-269) antibodyAQP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (C-Term) antibodyAQP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (C-Term) antibodyAQP1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 220-269) antibodyAQP1 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) antibodyAQP1 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 209-301) antibodyAQP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 2-269) antibodyAQP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 1-10) antibodyAQP1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 1 (Colton Blood Group) (AQP1) (AA 241-269) antibodyAQP1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:400
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说明
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Cited Application: IHC|Whole Tissue Staining
Negative Control: (ABIN7234751)
Blocking Peptide: (ABIN7234751)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))
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别名
- AQP1
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背景
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AQP1, Aquaporin-CHIP, CHIP28, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule,Aquaporin 1 (AQP-1) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12).The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. AQP-1 together with AQP-2, AQP-4 and AQP-5 belongs to the first group1.Little is known about the function of the two newest members, AQP-11 and AQP-12.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit, contains four pores1.AQP-1 is widely expressed in several organs with prominent expression found in kidney, lung, red blood cells intestine and brain. Studies with mice lacking AQP-1 show that the channel has a critical role in urine concentration2. In addition, AQP-1 expression in tumor cells was shown to contribute to enhanced tumor spread and metastatic potential3.
Alternative names: Aquaporin 1, AQP1, Aquaporin-CHIP, CHIP28, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule -
基因ID
- 358
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NCBI登录号
- NM_198098
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UniProt
- P29972
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途径
- Hormone Transport
抗原
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