ADCYAP1R1 抗体 (Intracellular)
Quick Overview for ADCYAP1R1 抗体 (Intracellular) (ABIN7042894)
抗原
See all ADCYAP1R1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 474-487, Intracellular
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原理
- A Rabbit Polyclonal Antibody to PACAP Type I Receptor
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特异性
- Intracellular, C-terminus
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交叉反应
- 小鼠, 大鼠
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预测反应
- Mouse - identical, human - 12,14 amino acid residues identical
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产品特性
- Anti-PACAP Receptor 1 (PAC1) Antibody is directed against an epitope of the rat PACAP type I receptor. Anti-PACAP Receptor 1 (PAC1) Antibody (ABIN7042894, ABIN7045333 and ABIN7045334) can be used in western blot and immunohistochemistry applications. It has been designed to recognize PAC1 receptor from rat, mouse and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KVNRYFTMDFKHRH, corresponding to amino acid residues 474-487 of rat PAC1 receptor
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亚型
- IgG
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anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) antibody
ADCYAP1R1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) antibodyADCYAP1R1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (N-Term) antibodyADCYAP1R1 适用: 人, Cow, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (N-Term) antibodyADCYAP1R1 适用: 人, 猴 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (AA 21-120) antibodyADCYAP1R1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (AA 251-330) antibodyADCYAP1R1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (C-Term) antibodyADCYAP1R1 适用: 人, 犬, 猴, Bat, 小鸡, 非洲爪蟾 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (C-Term) antibodyADCYAP1R1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (AA 343-392) antibodyADCYAP1R1 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 豚鼠, 马, 兔, 绵羊, 斑马鱼, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) (C-Term) antibodyADCYAP1R1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:400
Application Dilutions Western blot wb: 1:500
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说明
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Cited Application: IHC
Negative Control: (ABIN7234650)
Blocking Peptide: (ABIN7234650)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))
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别名
- ADCYAP1R1
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背景
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PACAP type I receptor, Pituitary adenylate cyclase-activating polypeptide type I receptor, PACAP-R1, ADCYAP1R1,Pituitary adenylate cyclase-activating polypeptide (PACAP, encoded by ADCYAP1) belongs a superfamily of structurally related peptide hormones, which include vasoactive intestinal peptide (VIP), glucagon, glucagon-like peptides, secretin, gastric inhibitory peptide and growth hormone-releasing hormone.PACAP acts through PAC1, VPAC1 and VPAC2, initiating multiple signaling pathways1. PAC1 is a class B member of the G-protein coupled receptors (GPCRs) superfamily. Class B receptors are differentiated from Class A by a relatively large N-terminal ectodomain that is crucial to ligand recognition2.PAC1R is mainly expressed on smooth muscle cells, neurons, endothelial cells and peritoneal macrophages3.PAC1R is associated with posttraumatic stress disorder (PTSD) symptoms and psychophysiological markers of fear and anxiety4.PAC1 receptor null mice demonstrate reduced anxiety-like behavior5. In addition, PAC1 overexpression can result in hydrocephalus- and schizophrenia-related neuropathology1.
Alternative names: PACAP Receptor 1 (PAC1), PACAP type I receptor, Pituitary adenylate cyclase-activating polypeptide type I receptor, PACAP-R1, ADCYAP1R1 -
基因ID
- 24167
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NCBI登录号
- NM_001118
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UniProt
- P32215
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途径
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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