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ARNTL 抗体 (AA 151-250) (Cy7)

This anti-ARNTL antibody is a 兔 多克隆 antibody detecting ARNTL in WB, FACS, IF (cc) 和 IF (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN703577
发货至: 中国

Quick Overview for ARNTL 抗体 (AA 151-250) (Cy7) (ABIN703577)

抗原

See all ARNTL 抗体
ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

适用

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  • 1
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人, 大鼠, 小鼠

宿主

  • 61
  • 9
  • 3

克隆类型

  • 57
  • 16
多克隆

标记

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  • 1
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This ARNTL antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 4
    • 3
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    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
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    AA 151-250

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human BMAL1

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

    别名

    BMAL1

    背景

    Synonyms: ARNT like protein 1 brain and muscle, ARNTL, Aryl hydrocarbon receptor nuclear translocator like, Aryl hydrocarbon receptor nuclear translocator like protein 1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, Basic helix loop helix PAS orphan MOP3, bHLH PAS protein JAP3, bHLHe5, BMAL 1, BMAL1c, Brain and muscle ARNT like 1, cycle, JAP 3, JAP3, Member of PAS protein 3, Member of PAS superfamily 3, MOP3, PAS domain-containing protein 3, PASD 3, PASD3, TIC.

    Background: Component of the circadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Efficient DNA binding requires dimerization with another bHLH protein. Heterodimerization with CLOCK is required for E-box-dependent transactivation, for CLOCK nuclear translocation and degradation, and, for phosphorylation of both CLOCK and ARNTL. Interaction with PER and CRY proteins requires translocation to the nucleus. Interaction of the CLOCK-ARNTL heterodimer with PER or CRY inhibits transcription activation. Interacts with HSP90, with AHR in vitro, but not in vivo.

    基因ID

    406

    途径

    Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
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