Tumor Protein p73 抗体 (pTyr99) (FITC)
Quick Overview for Tumor Protein p73 抗体 (pTyr99) (FITC) (ABIN703112)
抗原
See all Tumor Protein p73 (TP73) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr99
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human p73 around the phosphorylation site of Tyr99 [SP(p-Y)AQ]
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亚型
- IgG
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anti-Tumor Protein P73 (TP73) (AA 167-409) antibody
TP73 适用: 人 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-Tumor Protein P73 (TP73) (acLys321) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (Tyr221) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (pTyr99) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 288-317) antibodyTP73 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 501-631) antibodyTP73 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 167-409) antibodyTP73 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-100) antibodyTP73 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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别名
- p73
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背景
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Synonyms: p73Tyr99, TP73phospho Y99, p53 like transcription factor, p53 Related Protein, p73, TP 73, TP73, Tumor Protein p73, P73_HUMAN.
Background: P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
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基因ID
- 7161
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途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
抗原
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