VASP 抗体 (AA 251-350) (Cy7)
Quick Overview for VASP 抗体 (AA 251-350) (Cy7) (ABIN701461)
抗原
See all VASP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-350
-
预测反应
- Human,Mouse,Rat,Dog,Cow
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human VASP
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
-
别名
- VASP
-
背景
-
Synonyms: Vasodilator stimulated phosphoprotein_ Vasodilator-stimulated phosphoprotein_ VASP_ VASP_HUMAN.
Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
-
基因ID
- 7408
-
途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
抗原
-