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CD2 抗体

The 大鼠 单克隆 anti-CD2 antibody is suitable to detect CD2 in samples from 小鼠. It has been validated for FACS, IP 和 Func.
产品编号 ABIN7013989
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD2 抗体 (ABIN7013989)

抗原

See all CD2 抗体
CD2

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

RM2-5
  • 原理

    Anti-Ms CD2 Purified Low Endotoxin

    特异性

    The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

    纯化方法

    Purified by protein-G affinity chromatography.

    内毒素水平

    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

    免疫原

    murine thymocytes

    亚型

    IgG2b lambda
  • 应用备注

    Functional application: Blocking.
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD2

    别名

    CD2

    背景

    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37

    基因ID

    12481

    UniProt

    P08920
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