CD2 抗体
Quick Overview for CD2 抗体 (ABIN7013989)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ms CD2 Purified Low Endotoxin
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特异性
- The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
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纯化方法
- Purified by protein-G affinity chromatography.
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内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
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免疫原
- murine thymocytes
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亚型
- IgG2b lambda
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应用备注
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD2
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别名
- CD2
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背景
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37
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基因ID
- 12481
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UniProt
- P08920
抗原
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