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ITGA4 抗体

This 大鼠 单克隆 antibody specifically detects ITGA4 in FACS, IP, IHC (fro) 和 Func. It exhibits reactivity toward 小鼠.
产品编号 ABIN7013910
发货至: 中国
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Quick Overview for ITGA4 抗体 (ABIN7013910)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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小鼠

宿主

  • 74
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  • 34
大鼠

克隆类型

  • 119
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  • 2
单克隆

标记

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This ITGA4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

DATK32
  • 原理

    Anti-Ms LPAM-1 Purified Azide Free

    特异性

    The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.

    纯化方法

    Purified by protein-G affinity chromatography.

    免疫原

    TK1 cells

    亚型

    IgG2a kappa
  • 应用备注

    Functional application: Blocking of cell adhesion.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    LPAM-1

    背景

    Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Llmphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.,Integrin alpha 4 beta 7, CD49d / Ly69

    途径

    Integrin Complex
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