ITGA4 抗体
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北京 101111
Quick Overview for ITGA4 抗体 (ABIN7013910)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ms LPAM-1 Purified Azide Free
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特异性
- The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex, which is expressed on the majority of peripheral lymphocytes, as well as on subsets of thymocytes and bone marrow cells.
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纯化方法
- Purified by protein-G affinity chromatography.
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免疫原
- TK1 cells
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亚型
- IgG2a kappa
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应用备注
- Functional application: Blocking of cell adhesion.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- ITGA4 (Integrin alpha 4 (ITGA4))
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别名
- LPAM-1
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背景
- Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Llmphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.,Integrin alpha 4 beta 7, CD49d / Ly69
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途径
- Integrin Complex
抗原
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