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Aurora A 抗体 (pThr198, pThr232, pThr288)

This anti-Aurora A antibody is a 兔 多克隆 antibody detecting Aurora A in WB. Suitable for 人 和 大鼠.
产品编号 ABIN7265292
发货至: 中国

Quick Overview for Aurora A 抗体 (pThr198, pThr232, pThr288) (ABIN7265292)

抗原

See all Aurora A (AURKA) 抗体
Aurora A (AURKA) (Aurora Kinase A (AURKA))

适用

  • 118
  • 68
  • 40
  • 21
  • 18
  • 16
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
人, 大鼠

宿主

  • 114
  • 19
  • 1

克隆类型

  • 104
  • 29
多克隆

标记

  • 85
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aurora A antibody is un-conjugated

应用范围

  • 99
  • 55
  • 39
  • 29
  • 16
  • 14
  • 11
  • 11
  • 10
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 21
    • 11
    • 9
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr198, pThr232, pThr288

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding T288/T232/T198 of human AURKA/AURKB/AURKC.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    别名

    AURKA

    背景

    The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene./This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. /This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

    分子量

    35K kDa/48 kDa

    基因ID

    6790, 9212, 6795

    UniProt

    O14965, Q96GD4, Q9UQB9

    途径

    Cell Division Cycle, Asymmetric Protein Localization
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