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Phospholamban 抗体 (pThr17)

This anti-Phospholamban antibody is a 兔 多克隆 antibody detecting Phospholamban in IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7265288
发货至: 中国

Quick Overview for Phospholamban 抗体 (pThr17) (ABIN7265288)

抗原

See all Phospholamban (PLN) 抗体
Phospholamban (PLN)

适用

  • 86
  • 23
  • 21
  • 3
  • 2
  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 87
  • 3
  • 1

克隆类型

  • 86
  • 5
多克隆

标记

  • 44
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This Phospholamban antibody is un-conjugated

应用范围

  • 37
  • 36
  • 26
  • 26
  • 21
  • 11
  • 10
  • 9
  • 9
  • 9
  • 7
  • 6
  • 1
  • 1
Immunohistochemistry (IHC)
  • 抗原表位

    • 26
    • 17
    • 11
    • 9
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr17

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding T17 of human PLN

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Phospholamban (PLN)

    别名

    PLN

    背景

    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.

    基因ID

    5350

    UniProt

    P26678

    途径

    Negative Regulation of Transporter Activity
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