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ZAP70 抗体 (pTyr493)

Name: ZAP70 抗体 (pTyr493)
Brand: antibodies-online
SKU: ABIN7265210
Availability: OutOfStock

This anti-ZAP70 antibody is a 兔多克隆 antibody detecting ZAP70 in WB 和 IHC. Suitable for 人, 小鼠和大鼠.

Western blot analysis of extracts of Jurkat cells using Phospho-ZAP70(Y493) Polyclonal Antibody at dilution of 1:5000. (ZAP70 抗体 (pTyr493))

Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue, using Phospho-ZAP70(Y493) Polyclonal Antibody (ZAP70 抗体 (pTyr493))

IHC (p)

2 images

产品编号 ABIN7265210

发货至: 中国

Datasheet as PDF

Quick Overview for ZAP70 抗体 (pTyr493) (ABIN7265210)

抗原

See all ZAP70 抗体

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This ZAP70 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product ZAP70 Primary Antibody

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pTyr493

产品特性

Phosphorylated antibody

纯化方法

Affinity purification

免疫原

A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70

亚型

IgG
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (C-Term) antibody
ZAP70 适用: 人 WB, ICC, ICFC 宿主: 小鼠 Monoclonal ZAP-03 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr319) antibody
ZAP70 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibody
ZAP70 适用: 人 IHC, FACS, ELISA, IF, StM, Coat 宿主: 小鼠 Monoclonal ZAP70-2035 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibody
ZAP70 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 1F3G9 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 337-600) antibody
ZAP70 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-254) antibody
ZAP70 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 2F3-2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody
ZAP70 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibody
ZAP70 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D9C2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibody
ZAP70 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal ZAP70-2046 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-300) antibody
ZAP70 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:2000-1:5000 IHC 1:50-1:100

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

别名

ZAP70

背景

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

分子量

Observed_MW: 70 kDa
Calculated_MW: 35 kDa/55 kDa/69 kDa

基因ID

7535

UniProt

P43403

途径

TCR Signaling, Ubiquitin Proteasome Pathway