电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ZAP70 抗体 (pTyr493)

ZAP70 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7265210
发货至: 中国
  • 抗原 See all ZAP70 抗体
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    抗原表位
    • 33
    • 33
    • 25
    • 20
    • 17
    • 16
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr493
    适用
    • 252
    • 122
    • 46
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 187
    • 61
    • 2
    • 2
    • 1
    克隆类型
    • 180
    • 72
    多克隆
    标记
    • 131
    • 13
    • 12
    • 9
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This ZAP70 antibody is un-conjugated
    应用范围
    • 177
    • 112
    • 85
    • 55
    • 52
    • 52
    • 43
    • 23
    • 22
    • 20
    • 13
    • 12
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Phosphorylated antibody
    纯化方法
    Affinity purification
    免疫原
    A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70
    亚型
    IgG
    Top Product
    Discover our top product ZAP70 Primary Antibody
  • 应用备注
    WB 1:2000-1:5000 IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    别名
    ZAP70 (ZAP70 产品)
    背景
    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
    分子量

    Observed_MW: 70 kDa

    Calculated_MW: 35 kDa/55 kDa/69 kDa

    基因ID
    7535
    UniProt
    P43403
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
You are here:
客服