Cofilin 抗体 (pSer3)
Quick Overview for Cofilin 抗体 (pSer3) (ABIN7265124)
抗原
See all Cofilin (CFL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer3
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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别名
- CFL1
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背景
- The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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分子量
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Observed_MW: 18 kDa
Calculated_MW: 18 kDa
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基因ID
- 1072
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UniProt
- P23528
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途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
抗原
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