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CDK1 抗体 (pTyr15)

This anti-CDK1 antibody is a 兔 多克隆 antibody detecting CDK1 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7265020
发货至: 中国

Quick Overview for CDK1 抗体 (pTyr15) (ABIN7265020)

抗原

See all CDK1 抗体
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pTyr15

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around Y15 of human CDK1 (NP_001777.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDK1

    背景

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 34 kDa

    Calculated_MW: 27 kDa/34 kDa

    基因ID

    983

    UniProt

    P06493

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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