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Ribonuclease H1 抗体

This 兔 多克隆 antibody specifically detects Ribonuclease H1 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7264745
发货至: 中国
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Quick Overview for Ribonuclease H1 抗体 (ABIN7264745)

抗原

See all Ribonuclease H1 (RNASEH1) 抗体
Ribonuclease H1 (RNASEH1)

适用

  • 17
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 12
  • 5

克隆类型

  • 14
  • 3
多克隆

标记

  • 14
  • 1
  • 1
  • 1
This Ribonuclease H1 antibody is un-conjugated

应用范围

  • 13
  • 10
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human RNASEH1 (NP_002927.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Ribonuclease H1 (RNASEH1)

    别名

    RNASEH1

    背景

    This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes, two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.

    分子量

    Observed_MW: 37 kDa

    Calculated_MW: 32 kDa

    基因ID

    246243

    UniProt

    O60930
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