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MDC1 抗体

This anti-MDC1 antibody is a 兔 多克隆 antibody detecting MDC1 in IHC 和 IF. Suitable for 人.
产品编号 ABIN7264389
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MDC1 抗体 (ABIN7264389)

抗原

See all MDC1 抗体
MDC1 (Mdc1 (MDC1))

适用

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宿主

  • 48
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克隆类型

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多克隆

标记

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This MDC1 antibody is un-conjugated

应用范围

  • 57
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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human MDC1 (NP_055456.2).

    亚型

    IgG
  • 应用备注

    IHC 1:100-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MDC1 (Mdc1 (MDC1))

    别名

    MDC1

    背景

    The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

    基因ID

    9656

    UniProt

    Q14676
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