PDE6A 抗体
Quick Overview for PDE6A 抗体 (ABIN7263957)
抗原
See all PDE6A 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human PDE6A (NP_000431.2).
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亚型
- IgG
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anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 656-860) antibody
PDE6A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 656-860) antibodyPDE6A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (N-Term) antibodyPDE6A 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
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别名
- PDE6A
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背景
- This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
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分子量
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Observed_MW: 120 kDa
Calculated_MW: 99 kDa
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基因ID
- 5145
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UniProt
- P16499
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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