GTF2A2 抗体
Quick Overview for GTF2A2 抗体 (ABIN7263683)
抗原
See all GTF2A2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            产品特性
- Polyclonal Antibody
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                                            纯化方法
- Affinity purification
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                                            免疫原
- Recombinant fusion protein of human GTF2A2 (NP_004483.1).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB 1:500-1:2000
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))
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                                            别名
- GTF2A2
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                                            背景
- Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP, MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF, MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).
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                                            分子量
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                        Observed_MW: 12 kDa Calculated_MW: 12 kDa 
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                                            基因ID
- 2958
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                                            UniProt
- P52657
 抗原
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