PPP2R1B 抗体
Quick Overview for PPP2R1B 抗体 (ABIN7262595)
抗原
See all PPP2R1B 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human PPP2R1B (NP_859050.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PPP2R1B (Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))
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别名
- PPP2R1B
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背景
- This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
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分子量
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Observed_MW: 65 kDa
Calculated_MW: 52 kDa/61 kDa/66 kDa/73 kDa
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基因ID
- 5519
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UniProt
- P30154
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途径
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
抗原
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