Adenylosuccinate Lyase 抗体
Quick Overview for Adenylosuccinate Lyase 抗体 (ABIN7262084)
抗原
See all Adenylosuccinate Lyase (ADSL) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human ADSL (NP_000017.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IF 1:20-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Adenylosuccinate Lyase (ADSL)
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别名
- ADSL
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背景
- The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.
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分子量
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Observed_MW: 55 kDa
Calculated_MW: 48 kDa/54 kDa
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基因ID
- 158
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UniProt
- P30566
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途径
- Ribonucleoside Biosynthetic Process
抗原
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