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FUBP1 抗体

This anti-FUBP1 antibody is a 兔 多克隆 antibody detecting FUBP1 in IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7261534
发货至: 中国

Quick Overview for FUBP1 抗体 (ABIN7261534)

抗原

See all FUBP1 抗体
FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

适用

  • 46
  • 23
  • 22
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 40
  • 6
  • 1

克隆类型

  • 29
  • 18
多克隆

标记

  • 32
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FUBP1 antibody is un-conjugated

应用范围

  • 38
  • 24
  • 16
  • 13
  • 9
  • 7
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human FUBP1 (NP_003893.2).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200 IF 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

    别名

    FUBP1

    背景

    The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants.

    基因ID

    8880

    UniProt

    Q96AE4
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