Glutaredoxin 1 抗体
Quick Overview for Glutaredoxin 1 抗体 (ABIN7261263)
抗原
See all Glutaredoxin 1 (GRX1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein of human GLRX (NP_001112362.1).
-
亚型
- IgG
-
-
-
-
应用备注
- IHC 1:50-1:200 IF 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Glutaredoxin 1 (GRX1)
-
别名
- GLRX
-
背景
- This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
-
基因ID
- 2745
-
UniProt
- P35754
-
途径
- Cell RedoxHomeostasis
抗原
-