RBM15 抗体
Quick Overview for RBM15 抗体 (ABIN7261163)
抗原
See all RBM15 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            产品特性
- Polyclonal Antibody
- 
                                            纯化方法
- Affinity purification
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                                            免疫原
- Recombinant fusion protein of human RBM15 (NP_001188474.1).
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB 1:500-1:2000
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - RBM15 (RNA Binding Motif Protein 15 (RBM15))
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                                            别名
- RBM15
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                                            背景
- RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5' translocation partner of the MAL gene in t(1,22)(p13,q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
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                                            分子量
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                        Observed_MW: 120 kDa Calculated_MW: 99 kDa/104 kDa/106 kDa/107 kDa 
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                                            基因ID
- 64783
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                                            UniProt
- Q96T37
 抗原
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