HMGCS1 抗体
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北京 101111
Quick Overview for HMGCS1 抗体 (ABIN7260905)
抗原
See all HMGCS1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human HMGCS1 (NP_002121.4).
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亚型
- IgG
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anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-238) antibody
HMGCS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 293-467) antibodyHMGCS1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 241-520) antibodyHMGCS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 360-520) antibodyHMGCS1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) antibodyHMGCS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (Internal Region) antibodyHMGCS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 290-317) antibodyHMGCS1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20146 unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 251-300) antibodyHMGCS1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, Hamster, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-520) antibodyHMGCS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 442-470), (C-Term) antibodyHMGCS1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20147 unconjugated
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应用备注
- IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
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别名
- HMGCS1
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背景
- HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
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基因ID
- 3157
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UniProt
- Q01581
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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