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GSTM3 抗体

This anti-GSTM3 antibody is a 兔 多克隆 antibody detecting GSTM3 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN7260901
发货至: 中国

Quick Overview for GSTM3 抗体 (ABIN7260901)

抗原

See all GSTM3 抗体
GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

适用

  • 30
  • 10
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 22
  • 9
  • 2

克隆类型

  • 26
  • 7
多克隆

标记

  • 29
  • 2
  • 1
  • 1
This GSTM3 antibody is un-conjugated

应用范围

  • 25
  • 16
  • 15
  • 7
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human GSTM3 (NP_000840.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

    别名

    GSTM3

    背景

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

    分子量

    Observed_MW: 25 kDa

    Calculated_MW: 26 kDa

    基因ID

    2947

    UniProt

    P21266
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