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CSTB 抗体

This anti-CSTB antibody is a 兔 多克隆 antibody detecting CSTB in WB, IHC 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN7260869
发货至: 中国

Quick Overview for CSTB 抗体 (ABIN7260869)

抗原

See all CSTB 抗体
CSTB (Cystatin B (Stefin B) (CSTB))

适用

  • 92
  • 29
  • 24
  • 13
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 大鼠

宿主

  • 101
  • 24
  • 1
  • 1

克隆类型

  • 97
  • 29
多克隆

标记

  • 65
  • 19
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CSTB antibody is un-conjugated

应用范围

  • 86
  • 59
  • 36
  • 34
  • 22
  • 18
  • 13
  • 13
  • 11
  • 10
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human CSTB (NP_000091.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CSTB (Cystatin B (Stefin B) (CSTB))

    别名

    CSTB

    背景

    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.

    分子量

    Observed_MW: 14 kDa

    Calculated_MW: 11 kDa

    基因ID

    1476

    UniProt

    P04080

    途径

    Response to Water Deprivation
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