Importin 5 抗体
Quick Overview for Importin 5 抗体 (ABIN7260031)
抗原
See all Importin 5 (IPO5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein of human IPO5 (NP_002262.3).
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000 IF 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Importin 5 (IPO5)
-
别名
- IPO5
-
背景
- Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
-
分子量
-
Observed_MW: 124 kDa
Calculated_MW: 116 kDa/123 kDa/125 kDa
-
基因ID
- 3843
-
UniProt
- O00410
-
途径
- Protein targeting to Nucleus
抗原
-