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TERT 抗体

TERT 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259294
发货至: 中国
  • 抗原 See all TERT 抗体
    TERT (Telomerase Reverse Transcriptase (TERT))
    适用
    • 107
    • 39
    • 24
    • 5
    • 1
    • 1
    人, 小鼠
    宿主
    • 113
    • 8
    • 1
    克隆类型
    • 103
    • 19
    多克隆
    标记
    • 61
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TERT antibody is un-conjugated
    应用范围
    • 72
    • 50
    • 40
    • 27
    • 22
    • 17
    • 14
    • 13
    • 12
    • 10
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human TERT (NP_937983.2).
    亚型
    IgG
    Top Product
    Discover our top product TERT Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TERT (Telomerase Reverse Transcriptase (TERT))
    别名
    TERT (TERT 产品)
    背景
    Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
    基因ID
    7015
    UniProt
    O14746
    途径
    Telomere Maintenance
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