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IFI35 抗体

The 兔 多克隆 anti-IFI35 antibody is suitable to detect IFI35 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN7259096
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IFI35 抗体 (ABIN7259096)

抗原

See all IFI35 抗体
IFI35 (Interferon-Induced Protein 35 (IFI35))

适用

  • 37
  • 2
  • 2
人, 小鼠

宿主

  • 28
  • 9

克隆类型

  • 31
  • 6
多克隆

标记

  • 24
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFI35 antibody is un-conjugated

应用范围

  • 27
  • 13
  • 13
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human IFI35 (NP_005524.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IFI35 (Interferon-Induced Protein 35 (IFI35))

    别名

    IFI35

    背景

    The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.

    分子量

    Observed_MW: 35 kDa

    Calculated_MW: 31 kDa

    基因ID

    3430

    UniProt

    P80217
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