Glutathione Peroxidase 2 抗体
Quick Overview for Glutathione Peroxidase 2 抗体 (ABIN7258828)
抗原
See all Glutathione Peroxidase 2 (GPX2) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human GPX2 (NP_002074.2).
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亚型
- IgG
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anti-Glutathione Peroxidase 2 (GPX2) (AA 100-180) antibody
GPX2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 2 (GPX2) (C-Term) antibodyKO Validated GPX2 适用: 人 WB, ICC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 2 (GPX2) (Internal Region) antibodyVerified GPX2 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 2 (GPX2) (AA 71-168) antibodyGPX2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 2 (GPX2) (AA 92-141) antibodyGPX2 适用: 人, 小鼠, 大鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 2 (GPX2) (Middle Region) antibodyGPX2 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Glutathione Peroxidase 2 (GPX2)
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别名
- GPX2
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背景
- The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
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基因ID
- 2877
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UniProt
- P18283
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途径
- Thyroid Hormone Synthesis
抗原
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