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Glutathione Peroxidase 2 抗体

The 兔 多克隆 anti-Glutathione Peroxidase 2 antibody is suitable to detect Glutathione Peroxidase 2 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC.
产品编号 ABIN7258828
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Glutathione Peroxidase 2 抗体 (ABIN7258828)

抗原

See all Glutathione Peroxidase 2 (GPX2) 抗体
Glutathione Peroxidase 2 (GPX2)

适用

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人, 小鼠, 大鼠

宿主

  • 24
  • 1

克隆类型

  • 14
  • 11
多克隆

标记

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  • 2
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This Glutathione Peroxidase 2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human GPX2 (NP_002074.2).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Glutathione Peroxidase 2 (GPX2)

    别名

    GPX2

    背景

    The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

    基因ID

    2877

    UniProt

    P18283

    途径

    Thyroid Hormone Synthesis
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