Acetyl-CoA Carboxylase alpha 抗体
Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (ABIN7258506)
抗原
See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human ACACA
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Acetyl-CoA Carboxylase alpha (ACACA)
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别名
- ACACA
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背景
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
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分子量
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Observed_MW: 240 kDa
Calculated_MW: 257 kDa/259 kDa/265 kDa/269 kDa
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基因ID
- 31
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UniProt
- Q13085
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途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
抗原
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