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Acetyl-CoA Carboxylase alpha 抗体

This anti-Acetyl-CoA Carboxylase alpha antibody is a 兔 多克隆 antibody detecting Acetyl-CoA Carboxylase alpha in WB 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7258506
发货至: 中国

Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (ABIN7258506)

抗原

See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
Acetyl-CoA Carboxylase alpha (ACACA)

适用

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人, 小鼠, 大鼠

宿主

  • 97
  • 6
  • 1

克隆类型

  • 90
  • 14
多克隆

标记

  • 61
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  • 1
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This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

应用范围

  • 91
  • 36
  • 34
  • 26
  • 17
  • 14
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  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide of human ACACA

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Acetyl-CoA Carboxylase alpha (ACACA)

    别名

    ACACA

    背景

    Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

    分子量

    Observed_MW: 240 kDa

    Calculated_MW: 257 kDa/259 kDa/265 kDa/269 kDa

    基因ID

    31

    UniProt

    Q13085

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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