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BAG3 抗体

This anti-BAG3 antibody is a 兔 多克隆 antibody detecting BAG3 in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7258158
发货至: 中国

Quick Overview for BAG3 抗体 (ABIN7258158)

抗原

See all BAG3 抗体
BAG3 (BCL2-Associated Athanogene 3 (BAG3))

适用

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人, 小鼠, 大鼠

宿主

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  • 4
  • 1

克隆类型

  • 52
  • 16
多克隆

标记

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This BAG3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human BAG3 (NP_004272.2).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BAG3 (BCL2-Associated Athanogene 3 (BAG3))

    别名

    BAG3

    背景

    BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

    基因ID

    9531

    UniProt

    O95817
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