DLAT 抗体
Quick Overview for DLAT 抗体 (ABIN7257932)
抗原
See all DLAT 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human DLAT (NP_001922.2).
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亚型
- IgG
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anti-Dihydrolipoyl Transacetylase (DLAT) (AA 368-626) antibody
DLAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 87-270) antibodyDLAT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-647) antibodyDLAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-647) antibodyDLAT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 579-607), (C-Term) antibodyDLAT 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26843 unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (N-Term) antibodyDLAT 适用: 人, 小鼠, 大鼠, 兔, 犬, 斑马鱼, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 26-217) antibodyDLAT 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyDLAT 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 61-110) antibodyDLAT 适用: 人, 小鼠, 大鼠, 兔, 犬, 斑马鱼, Cow, 豚鼠, 马, Pig, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-290) antibodyDLAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DLAT (Dihydrolipoyl Transacetylase (DLAT))
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别名
- DLAT
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背景
- This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.
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分子量
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Observed_MW: 69 kDa
Calculated_MW: 68 kDa
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基因ID
- 1737
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UniProt
- P10515
抗原
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