CAMLG 抗体
Quick Overview for CAMLG 抗体 (ABIN7257333)
抗原
See all CAMLG 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human CAMLG (NP_001736.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CAMLG (Calcium Modulating Ligand (CAMLG))
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别名
- CAMLG
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背景
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
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分子量
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Observed_MW: 38 kDa
Calculated_MW: 32 kDa
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基因ID
- 819
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UniProt
- P49069
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途径
- EGFR Signaling Pathway
抗原
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