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PIWIL4 抗体

This 兔 多克隆 antibody specifically detects PIWIL4 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7256712
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PIWIL4 抗体 (ABIN7256712)

抗原

See all PIWIL4 抗体
PIWIL4 (Piwi-Like 4 (PIWIL4))

适用

  • 29
  • 10
  • 10
  • 1
人, 小鼠, 大鼠

宿主

  • 27
  • 2

克隆类型

  • 28
  • 1
多克隆

标记

  • 12
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This PIWIL4 antibody is un-conjugated

应用范围

  • 12
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human PIWIL4 (NP_689644.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PIWIL4 (Piwi-Like 4 (PIWIL4))

    别名

    PIWIL4

    背景

    PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.

    分子量

    Observed_MW: 105 kDa

    Calculated_MW: 52 kDa/56 kDa/96 kDa

    基因ID

    143689

    UniProt

    Q7Z3Z4
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