RAG2 抗体
Quick Overview for RAG2 抗体 (ABIN7256152)
抗原
See all RAG2 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human RAG2 (NP_001230715.1).
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亚型
- IgG
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anti-Recombination Activating Gene 2 (RAG2) (Center) antibody
RAG2 适用: 人, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 1-527) antibodyRAG2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 428-527) antibodyRAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 258-527) antibodyRAG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 498-527), (C-Term) antibodyRAG2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (N-Term) antibodyRAG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 1-527) antibodyRAG2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 350-527) antibodyRAG2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4D5 unconjugated
anti-Recombination Activating Gene 2 (RAG2) (AA 296-415) antibodyRAG2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Activating Gene 2 (RAG2) (C-Term) antibodyRAG2 适用: 人, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RAG2 (Recombination Activating Gene 2 (RAG2))
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别名
- RAG2
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背景
- This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms.
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分子量
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Observed_MW: 59 kDa
Calculated_MW: 59 kDa
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基因ID
- 5897
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UniProt
- P55895
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途径
- Chromatin Binding, Production of Molecular Mediator of Immune Response
抗原
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