KIF14 抗体
Quick Overview for KIF14 抗体 (ABIN7255237)
抗原
See all KIF14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein of human KIF14 (NP_055690.1).
-
亚型
- IgG
-
-
anti-Kinesin Family Member 14 (KIF14) (AA 1399-1648) antibody
KIF14 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 14 (KIF14) (AA 261-531) antibodyKIF14 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 14 (KIF14) (N-Term) antibodyKIF14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC 1:50-1:200 IF 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- KIF14 (Kinesin Family Member 14 (KIF14))
-
别名
- KIF14
-
背景
- This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.
-
基因ID
- 9928
-
UniProt
- Q15058
抗原
-
