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MUC16 抗体

This anti-MUC16 antibody is a 兔 多克隆 antibody detecting MUC16 in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7255099
发货至: 中国

Quick Overview for MUC16 抗体 (ABIN7255099)

抗原

See all MUC16 (CA125) 抗体
MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

适用

人, 小鼠, 大鼠

宿主

  • 70
  • 60
  • 2
  • 2
  • 1

克隆类型

  • 87
  • 43
  • 3
多克隆

标记

  • 63
  • 20
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This MUC16 antibody is un-conjugated

应用范围

  • 72
  • 52
  • 39
  • 32
  • 16
  • 10
  • 9
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human MUC16 (NP_078966.2).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

    别名

    MUC16

    背景

    This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.

    基因ID

    94025

    UniProt

    Q8WXI7
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