T-Box 1 抗体
Quick Overview for T-Box 1 抗体 (ABIN7254388)
抗原
See all T-Box 1 (TBX1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Antigen affinity purification
-
免疫原
- Synthetic peptide of human TBX1
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.7 mg/mL
-
缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- T-Box 1 (TBX1)
-
别名
- TBX1
-
背景
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
-
分子量
-
Observed_MW: Refer to figures
Calculated_MW: 43 kDa
-
UniProt
- O43435
-
途径
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
抗原
-